VISDB Viral Integration Site DataBase

VIS ID

TVIS42000456

Fusion event

EBV-GDF11 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

42242

Orient

+

Integrated sequence

TGCATGGAAATGGTACCCTGCATCCTGTGTTGGAGCTAGCAGCAAGAGAAACACCTCTCCGCCTTTCGCCAGAGGACACTGTAGTTCTGCGTTATCATGT| |GTTGCTTGAGGAGATAATTGAACGAAATTCAGAGACATTTACAGAAACTTGGAACAGATTTATAACACACACCGAACATGTGGATCTGGATTTTAACTCA

Chromosome

chr12

Cytoband

q13.2

Reference genome

Start

End

56140908/55747124 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-423-5p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-17-5p ; hsa-let-7b-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-142-5p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-519c-3p ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-519a-3p ; hsa-mir-302e ; hsa-mir-3912-5p ; hsa-mir-371b-3p ; hsa-mir-5590-3p ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-452-3p ; hsa-mir-3934-3p ; hsa-mir-6834-3p ; hsa-mir-4760-3p ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-4313 ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-8485

Nearest miRNA

hsa-mir-1244-3/Upstream/1409810; hsa-let-7i/Downstream/1447380;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/3124, chr12-CpG: 17/Downstream/70417

Upstream sequence

gttcaagagcaacatggccaacatgctgaaatcctgtctctaccaaaaatacaaaaaattagctggtcgtggtggcacatgcctgtaatctgagttactc

Downstream sequence

ggaaggttgaggcaggagaagagcttgaaaccaggaggcggaggctgcagtgagccgagattgcaccactgcactccagcctgagtgacagagcgagact