VISDB Viral Integration Site DataBase

VIS ID

TVIS42000473

Fusion event

EBV-TMEM132B integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

123595

Orient

+

Integrated sequence

CCTGTGCCTGGCCCTCTCCCCGGCATCCCTGCCAATGTAAATATCATAAAGGGGGTGCAGCTCCAGCCGCAGCAGGTCATAATTGGACGGGTGGAGGAAG| |TCTTCGGTGGGCAGCCCGCACTTGAGAGCTATATCTGTCACGGGGGCTGCATACTTGTTATCATAGAACTCGTCCACAATAACAAGCACATTCATGTGAT

Chromosome

chr12

Cytoband

q24.31

Reference genome

Start

End

125743223/125258677 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-221-3p ; hsa-mir-181a-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-567 ; hsa-mir-602 ; hsa-mir-8485 ; hsa-mir-377-3p ; hsa-mir-744-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-378a-5p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-6131 ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-505-3p ; hsa-mir-4735-5p ; hsa-mir-4762-5p ; hsa-mir-1208 ; hsa-mir-1273f ; hsa-mir-1291 ; hsa-mir-1304-3p ; hsa-mir-328-3p ; hsa-mir-4290 ; hsa-mir-4469 ; hsa-mir-6760-3p ; hsa-mir-6775-3p ; hsa-mir-6851-3p

Nearest miRNA

hsa-let-7i/Upstream/343018; hsa-mir-3612/Downstream/3035415;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/71111, chr12-CpG: 29/Downstream/72332

Upstream sequence

attccctctggggaagtggccagagaagatgaaacaaaaggagaagaatgcaaggaacctgcagcaggtggggttaaacctctagagaagggaaggcaag

Downstream sequence

aaatctctagtacaagggattatgcctcagccagcctctaaagaagggagggcaagaaatctctagtatgagggattgagcttaaccagcacccaagata