Basic Information
VIS ID
TVIS42000479
Fusion event
EBV-PDS5B integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
124663
Orient
+
Integrated sequence
CCTCTCAGTGAAGGTGGGATCCGCCAGGGTCTGCAGGATAAACATGGGAGGGGCATGGCGAAGCTTCACACTCAGGACGGTGTTAATGAGGCCCCTCTCC| |AGGGCATCGACCCCAAACTGTAGGGCCGAGGCCACGGTCTTGACAGCCCCCACGTACTCTGCGTACTCGACCGGGGTCTCGGGGATACTATGCAGGATCT
Host Sequence
Chromosome
chr13
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
33168007/32593870 (Hg38)
End
33168007/32593870 (Hg38)
Orient
-
Location type
Intronic
Target gene
PDS5B
miRNAs that regulate target gene
hsa-mir-27a-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-2276/Upstream/8431366; hsa-mir-1267/Downstream/7070164;
Nearest TSS
ENST00000623511/Upstream/7301; ENST00000481616/Downstream/107114;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/6172, chr13-CpG: 157/Downstream/421920
Nearest cancer related gene
PDS5B(TSG, No orient, 0)
Upstream sequence
AGGTCAGGAGAGATGCCTACTTATGTTCAAGTTTGCTCCAGTGTTCTGCGCAGAATCTTACCTTACGGGTTCACTTCGGTATTTCCAGCATTACCCATCA
Downstream sequence
TCATCTATCCATCCATCTACCTTtccattctttccagagatccttttgagtctctgctacatgccctgagtcctggactgggcactaagaacactgtagt
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate