VISDB Viral Integration Site DataBase

VIS ID

TVIS42000491

Fusion event

EBV-PCDH9 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

56225

Orient

+

Integrated sequence

CAGGAGGTCGTCAAAATCCATCACTGTTGGGAGGCTTGGGTCCTCAAGGTAGGAGAGATAATCGGAGGCCGCCGAGGCCACCTTGTCCCTGATGTCCGCC| |GTACACCTGCGCACGTGCAGGGCCGCATTCTTGGACCGGACGGCCACGTTGTGGACAAAGGGGGGCACTGAGGCGGCGGGAGGGGCCCCATACTCTATCG

Chromosome

chr13

Cytoband

q21.32

Reference genome

Start

End

67381323/66807191 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-188-5p ; hsa-mir-127-5p ; hsa-mir-4635 ; hsa-mir-7843-3p ; hsa-mir-4735-3p ; hsa-mir-1264 ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-548m

Nearest miRNA

hsa-mir-1297/Upstream/588867; hsa-mir-1267/Downstream/10890821;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/2962645, chr13-CpG: 92/Downstream/423185

Nearest cancer related gene

PCDH9(TSG, No orient, 0)

Upstream sequence

ttctgccaaggactctgccctaaccatctgcctagctagtttctttctacctcctCTCTTATTACAATTGTCTGCGacattcggtacaagtttgtagcct

Downstream sequence

aggagccataaactatatcatatagcctaggaatgtcataaggtatactatctgggcttgtgtaagtacgctgtatgatgtttgtgtgacaaagtcacct