VISDB Viral Integration Site DataBase

VIS ID

TVIS42000494

Fusion event

EBV-KLF12 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

36930

Orient

-

Integrated sequence

CTGCCACCTGCAACACTAACGGTGCCACCAAGGCCTACCCGTCCTACCACTCTGCCACCCACACCACTACTCACGGTACTACAAAGGCCTACCGAACTTC| |AACCCACACCATCACCACCACGCATGCATCTCCCTGTCTTGCATGTGCCAGACCAATCAATGCACCCTCTTACTCATCAAAGCACCCCAAATGATCCAGA

Chromosome

chr13

Cytoband

q22.1

Reference genome

Start

End

74399271/73825134 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-101-3p ; hsa-mir-23a-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-218-5p ; hsa-mir-4679 ; hsa-mir-4677-3p ; hsa-mir-216b-5p ; hsa-mir-1264 ; hsa-mir-6888-3p ; hsa-mir-4775 ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-34a-5p ; hsa-mir-141-3p ; hsa-mir-137 ; hsa-mir-200a-3p ; hsa-mir-4720-3p ; hsa-mir-4804-3p

Nearest miRNA

hsa-mir-1297/Upstream/7606810; hsa-mir-1267/Downstream/3872878;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/764902, chr13-CpG: 31/Downstream/308838

Upstream sequence

gtgtctatgttcattgggagtattggcccatatttttgttgttgttgtgtccttgtccagcttgggtaccagagtaatgctggttttgtagaacgagtta

Downstream sequence

acaagaattccatcttcttccatttttttggaatagtttgaagaaaattggtgttagttctttatacatttggtagaatttggcagtgagtccatctggt