Basic Information
VIS ID
TVIS42000514
Fusion event
EBV-ITPK1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
103756
Orient
-
Integrated sequence
ATCATGGCATCCGGCAAGCACCATCAGCCCGGGGGGACACGGAGCCTGACCATGCAAAAAGTAAGCCTGCGCGTGACCCCCCGCCTGGTGCTGGAAGTTA| |ACCGCCATAACGCCATCTGCGTGGCCACCAACGTCCCTGAGTTCTACAATGCCAGGGGGGACCTTAACATCCGAGACCTCCGGGCCCACGTCAAGGCCCG
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
93449239/92982894 (Hg38)
End
93449239/92982894 (Hg38)
Orient
+
Location type
Intronic
Target gene
ITPK1
miRNAs that regulate target gene
hsa-mir-421 ; hsa-mir-218-5p ; hsa-mir-6744-5p ; hsa-mir-4537 ; hsa-mir-6872-3p ; hsa-mir-6746-3p
Nearest miRNA
hsa-mir-1260a/Upstream/15716604; hsa-mir-1185-1/Downstream/965332;
Nearest TSS
ENST00000550708/Upstream/51217; ENST00000553639/Downstream/16045;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/59340, chr14-CpG: 44/Downstream/75528
Upstream sequence
TTGATAAATTTTAAAATTAGATTTTGTATTAAGAAGACTGTTCAGAAATTATCCCCATTATCTCATTTTTATTCATTATTCAAAGAAATGTAAGAAAATA
Downstream sequence
GCTAGCAGCTAGATCCTCACTTAGCTACCTGGTGACAGGCAAGCTGTGGAGAGAAAACACTGGAGGACGAGAAGAGAAGACAACAAATGCCACAGGTGCA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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