Basic Information
VIS ID
TVIS42000521
Fusion event
EBV-UNC13C integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
44037
Orient
+
Integrated sequence
GAGGTGCCCTGGAGCAGGAGATGCATGATTAGGCGCCCTTTTCCATTTGTGCTGAAGATGGGGCAGATGGTGCCACAAAAGTGTCCGGTGACCAGGTAAG| |CGTAGAGAAGGCTGGGTTGGGAAAGTCCAGCCTTTACTGCACTGGGAGAGCTGCTGAGCAGAGACACATAGAAGGTCTTGTTGGGTATTATCTTGTGGAC
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
54781269/54489071 (Hg38)
End
54781269/54489071 (Hg38)
Orient
+
Location type
Intronic
Target gene
UNC13C
miRNAs that regulate target gene
hsa-mir-128-3p
Nearest miRNA
hsa-mir-10393/Upstream/2211871; hsa-mir-11181/Downstream/883869;
Nearest TSS
ENST00000557528/Upstream/224926; ENST00000559093/Downstream/11900;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/729264, chr15-CpG: 52/Downstream/707473
Upstream sequence
gtgagccactgtgcctggccatttttttgtatttttagtagagatggggtttttccatgttggccaggctggtctcgaactcctgacctcaggtgatcca
Downstream sequence
TTAGGATATAATTGTAGTTTATTTTAAATATCTCCTGTATAATATGTGATTACTCATTATGGAAGGCATATATGAACACATAAGAAAAACAGGCACTTGG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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