Basic Information
VIS ID
TVIS42000524
Fusion event
EBV-MYO1E integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
101640
Orient
+
Integrated sequence
TCTAGGGCGGCGTCCGTAGAGCGACCATGACTGCTGACCCGCTGCGTCATATTTATGTGGCGGCTCTTGAACCCAAAGGCGCTATAGACGGTTGGGCAGT| |AGGCTCGGAGTGTCTGGGAGAGGTTCTGTGCGGCCACGGTTGTGGCTCCCGTGACCAGGCAGTCCATCGTGTGGTGGAGGCAGCTAACGCTGGTGCTCTT
Host Sequence
Chromosome
chr15
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
59660483/59368284 (Hg38)
End
59660483/59368284 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA15A
Target gene
MYO1E
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-30b-5p ; hsa-mir-93-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-10393/Upstream/197022; hsa-mir-11181/Downstream/2936374;
Nearest TSS
ENST00000557528/Upstream/103287; ENST00000558900/Downstream/4243;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/161145, chr15-CpG: 130/Downstream/3380
Upstream sequence
atgaacaaggacagcttggaggttaaaagcaagataaattcagttaagttaaatctctctcactgtcttttttttctttttttttttttttttttttttt
Downstream sequence
GGCCAGCCTCCCTCCACCAAATTATAAGACATTTAAGTTTGCAACCACTggccgggcacagtggctcatgcctgtaatcactttgggaggccgaggcagg
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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