VISDB Viral Integration Site DataBase

VIS ID

TVIS42000531

Fusion event

EBV-NTRK3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

71146

Orient

+

Integrated sequence

GTTGACTTGGTGAAAAACTCACGTAGTGTCTTGTAGCTCCTGCGCAGCTCGTGTCTGGGTTGCACTTTCTGCCAGGCTCCAATCTCTGGATGGGCGGCCA| |CCGCCAGCATCGACTGTAGGAACGGGTCTTGGATGGGCTCTAGGGTCAGAGAGGCCAGGGGGCTGGGCAAGGTGACAAATGTAATCTTGGAGACAGGCTT

Chromosome

chr15

Cytoband

q25.3

Reference genome

Start

End

88461245/87918014 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-765 ; hsa-mir-485-3p ; hsa-mir-128-3p ; hsa-mir-9-5p ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-617 ; hsa-mir-345-5p ; hsa-mir-384 ; hsa-mir-330-3p ; hsa-mir-198 ; hsa-mir-625-5p ; hsa-mir-509-3p ; hsa-mir-151a-3p ; hsa-mir-185-5p ; hsa-mir-768-5p ; hsa-mir-615-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-410-3p ; hsa-mir-4776-3p ; hsa-mir-192-3p

Nearest miRNA

hsa-mir-10393/Upstream/2092284; hsa-mir-11181/Downstream/28192;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/2077130, chr15-CpG: 36/Downstream/337409

Nearest cancer related gene

NTRK3(TSG, No orient, 0)

Upstream sequence

gctcacacctgtaatcccagcactttaggaggccaaggcagatagatcacctgaagtcagcagtttgaggccagcctggtcaacatggtgaaaccccatc

Downstream sequence

atttgtttgtttgtttTCATAGTTGCCCCTTACAAACTGCAAGTGGCTTTGAGCCTGTGGGACCAGCCAGTCTCCAGTTCGTAGTCCTGAGCCCATGgat