Basic Information
VIS ID
TVIS42000535
Fusion event
EBV-CACNA1H integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
127413
Orient
+
Integrated sequence
ACATCCGCCGACGTCTGGGCCTGGGCCGTGCTTCCGTAAAACGAGAGATTACCCTTCTCCTGGCCCACCTGCGCAAAAAGACAGCCCCCATCCACTGCCG| |TGATGCTCAAGTGTAAGCAGCCCGGGGCCCGCTTCATTCACGGGGCCGTGCACCTGCCATCGGGACAGATTGTCTTCCACACCATCCACAGCCCCACTCT
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1216869/1166869 (Hg38)
End
1216869/1166869 (Hg38)
Orient
+
Location type
Intronic
Target gene
CACNA1H
miRNAs that regulate target gene
hsa-mir-1226-5p ; hsa-mir-1268a ; hsa-mir-1268b ; hsa-mir-3616-3p ; hsa-mir-3937 ; hsa-mir-4511 ; hsa-mir-4710 ; hsa-mir-4721 ; hsa-mir-542-3p
Nearest miRNA
hsa-mir-3176/Upstream/396592; hsa-mir-11401/Downstream/568116;
Nearest TSS
ENST00000527434/Upstream/6693; ENST00000564954/Downstream/28160;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/8921, chr16-CpG: 28/Downstream/259
Upstream sequence
gccgcatgctagaagaacaggGCCTAAGTTGGGGGGCATCCTTCCAGGCTTTTCTGTAACCCCTAATTTTGGAGGGTACAGAGGCAGCTCTAGGTGCCCC
Downstream sequence
cgctgccgggccgtccctgctccaggttcgggggaaaccctggcttcgtgtctcttggacgtaaatctgggagcaaaattgctgggtcaggcggaaacag
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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