Basic Information
VIS ID
TVIS42000537
Fusion event
EBV-ACSM1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
7134
Orient
+
Integrated sequence
GGGAGGAGAAGAGAGGCTTCCCGCCTAGAGCATTTGCAAGTCAGGATTCTCTAATCCCTCTGGGAGAAGGGTATTCGGCTTGTCCGCTATTTTTTTGTGG| |CTAGTTTTGCACCCACAACATGTAAGGGCCCGCTACCCCTACAACACAAAACAAACTATCTCCCCTAACCATCCTTTTGCCAATCAATTCTGTGACAGGG
Host Sequence
Chromosome
chr16
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
20639067/20627745 (Hg38)
End
20639067/20627745 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACSM1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1225/Upstream/2133169; hsa-mir-11401/Downstream/878304;
Nearest TSS
ENST00000527434/Upstream/17502; ENST00000614721/Downstream/42110;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/278569, chr16-CpG: 65/Downstream/113579
Upstream sequence
TTTGAACTTCTTTAGAGAAGTATTATTTTTCTCTAATGAAATGCCTTCTCAATGGAAAAAAAAATGTGAATACCTGTTTGCAGTTTGCTATAAATATTTT
Downstream sequence
ttgaacctgggaggtggaggttgcagtgagccaagatcgcgccactgcaatccagcttgggcaacagagtgagacttcAtctctctctctctctctctct
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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