Basic Information
VIS ID
TVIS42000549
Fusion event
EBV-WWOX integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
127625
Orient
+
Integrated sequence
GGGACTGCCTGGGGAAAATGTACCCATCCCGGCCCTCTTCCGTGCCTCGGGCCTCAACGTCCGTGAGAGCCTACCCATGACCAACATGAGGGCACCGATC| |ATCTCGCTGGCTCGCCTCATCCTGGCCCCCAACCCCTATATCCTAGAGGGACAGCTGACGGTGGGCATGACACAGGACAACGGCATTCCCGTGCTTTTTG
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
78887359/78853462 (Hg38)
End
78887359/78853462 (Hg38)
Orient
+
Location type
Intronic
Target gene
WWOX
Nearest miRNA
hsa-mir-1225/Upstream/1984443; hsa-mir-11401/Downstream/2531556;
Nearest TSS
ENST00000527434/Upstream/346894; ENST00000566103/Downstream/224772;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/753293, chr16-CpG: 44/Downstream/736132
Nearest cancer related gene
WWOX(TSG, No orient, 0)
Upstream sequence
TCCAAATAAATCAAACTTTGAAACAAATATATAAATGGAATCAATCCAAATAAGAGATGATGTAGACAAGAGGGAGGATAATGGTAATAGTTTTTTAATC
Downstream sequence
TTAGTTATTGATCATCAAAATCCAGAAATCCAGTTTCAGCAAACATTCCATAACCCGGTGTGCTAAAACCCCCTCACTGCTCTCCATTACTCATGAATCT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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