Basic Information
VIS ID
TVIS42000573
Fusion event
EBV-TICAM1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
9271
Orient
+
Integrated sequence
CTTGAGGGTCCGCTTATCGGTAGCTACACAGGCCCCTCTGATTGACGTTGGTGTAGCCTCCCGTAGTCTTCCTGGGCCCCTGGGAGGTACATGTCCCCCA| |GCATTGGTGTAAGAGCTTCAGCCAAGAGTTACACATAAAGGCAATGTTGTGTTGCAGTCCACAGACTGCAAAGTCTGCTCCAGGATGAAAGCCACTCAGT
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
4815017/4815005 (Hg38)
End
4815017/4815005 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
TICAM1
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-193b-3p
Nearest miRNA
hsa-mir-1227/Upstream/44226; hsa-let-7e/Downstream/117682;
Nearest TSS
ENST00000633603/Upstream/19446; ENST00000591657/Downstream/2965;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/21800, chr19-CpG: 43/Downstream/16416
Upstream sequence
tgtggtgggcaagcctgggggtaagagaggactcagaccccatccccgccTGTGGGAGAGGTAGGATCAGAGACCACACTTCAGGGGGACAGGGCCCTCA
Downstream sequence
CATATGATCCGCTGAGGCCTTGAAACAACAGCCTCCACAGAcccatttctcagatgaaaaagcagaggctccgacaggggaggcacttgccaaatgtcac
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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