Basic Information
VIS ID
TVIS42000587
Fusion event
EBV-LTBP1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
148558
Orient
-
Integrated sequence
TTTGTTTTGGTGTTCGGCGCCAGGGTATCTCGACGTTGGAATGTCAACTCAACTTGGGCACCTCGATAACCGGCTCGTGGCTCGTACAGACGATTGTTTG| |GCTCTGTAACTTGCCAGGGACGGCTGACGATGTGTTTAGTCTGCCACTTGCATCCGGCGCTTTGGTTACTCGGGAGACTAATGGGGGGTGTGGTATGGCA
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
33367572/33142505 (Hg38)
End
33367572/33142505 (Hg38)
Orient
+
Location type
Intronic
Target gene
LTBP1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1301/Upstream/507174; hsa-mir-10b/Downstream/276011;
Nearest TSS
ENST00000437798/Upstream/7848; ENST00000413303/Downstream/101157;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/194408, chr2-CpG: 52/Downstream/456738
Upstream sequence
AAGAGAGAGTTTTGCACTGACTCTCATGCCTACTGTCTATACCCGTTTGCCATCTAGTCCCAGCTACTGTCACTCTCTGCTTCTGCTTCCATGGTACACT
Downstream sequence
AGACGAAGGGGTGCGTGGAAAGGTGATTCCATGGGTTACTTGGAACAAGAAGGGCAATAGGTTGACCTTAAGAGCCAGAATCAGGAGGGAATAAGGTCCT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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