Basic Information
VIS ID
TVIS42000590
Fusion event
EBV-THADA integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
130115
Orient
-
Integrated sequence
GGGTACAAAGTAGTTGTGAAAGTTGGCATAATGCACAAAGGTTGTAACAATCACCAGGGAATAGTCCCCGCTTTGGGCACTGGTTAAGGATGGGTAACTA| |AAAGGCCCCCTCAGATCCGGCAGGTCCTTCGTCTTGCCAAAGACCAGGCTCAACACATGCTCATCTCCCTTCTCGGTCACTCGCTTGTAGGTGCCCATCA
Host Sequence
Chromosome
chr2
Cytoband
p21
Reference genome
GRCh37/hg19
Start
43795980/43568841 (Hg38)
End
43795980/43568841 (Hg38)
Orient
+
Location type
Intronic
Target gene
THADA
miRNAs that regulate target gene
hsa-mir-505-3p ; hsa-mir-106b-5p ; hsa-let-7e-5p
Nearest miRNA
hsa-mir-1301/Upstream/8097355; hsa-mir-10b/Downstream/3808834;
Nearest TSS
ENST00000437798/Upstream/27538; ENST00000460356/Downstream/1674;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/341029, chr2-CpG: 42/Downstream/26948
Upstream sequence
ggatatgatgggcttgagtccctgcaatccatcagggttgaggggacaatgttggaaacactatatagtgcttaggattcttcaatgaaatttgggttgg
Downstream sequence
aaaccagcctgggtaacacagcaagaacctacatctacaaagaattaattaattaaaaaaaatttttttaaCTATCCTACACACACACTGGGGGCTTCAA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate