Basic Information
VIS ID
TVIS42000592
Fusion event
EBV-CD207 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
67701
Orient
+
Integrated sequence
CTTGTGATCATGGAAACCACTCAGACTCTCCGCTTTAAGACCAAGGCCCTAGCCGTCCTGTCCAAGTGCTATGACCATGCCCAGACTCATCTCAAGGGAG| |GAGTGCTGCAGGTAAACCTTCTGTCTGTAAACTATGGAGGCCCCCGGCTGGCCGCCGTGGCCAACGCAGGCACGGCCGGGCTAATCAGCTTCGAGGTCTC
Host Sequence
Chromosome
chr2
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
71057131/70830000 (Hg38)
End
71057131/70830000 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2E
Target gene
CD207
miRNAs that regulate target gene
hsa-mir-1224-5p ; hsa-mir-4710 ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-765 ; hsa-mir-7854-3p ; hsa-mir-4751 ; hsa-mir-5004-5p ; hsa-mir-5739 ; hsa-mir-6891-5p ; hsa-mir-3173-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/576995; hsa-mir-10b/Downstream/4260812;
Nearest TSS
ENST00000437798/Upstream/9400; ENST00000449073/Downstream/5822;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/39156, chr2-CpG: 22/Downstream/41607
Upstream sequence
CCTCTTCCTGTGTTAACCCCAACTCACAAAACACCAGCAGAGCCACGCAGGTGGCAGGCTGCCGACGCCTCACGGAGGCCAGGCTGGAGCGGGTTTTGTT
Downstream sequence
CATTGGAGACCTTGCTCTACTTTAATAAAAACTAGAGATAAGTACTGGTCACATTTTGTGGCATTTCCAGGACTGGAACTTCCCCAGTCCTTGTTATTTT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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