Basic Information
VIS ID
TVIS42000604
Fusion event
EBV-CCDC138 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
97924
Orient
+
Integrated sequence
CAATCAGACATGCGACGGCTTTAGCCTGGCCTCCTTAAATTCACCTAAGAATGGGAGCAACCAGCTGGTCATCAGCCGCTGCGCAAACGGACTCAACGTG| |GTCTCCTTCTTTATCTCCATCCTGAAGCGAAGCAGCTCCGCCCTCACGGGCCATCTCCGTGAGTTGTTAACCACCCTGGAGACTCTTTACGGTTCATTCT
Host Sequence
Chromosome
chr2
Cytoband
q13
Reference genome
GRCh37/hg19
Start
109424876/108808420 (Hg38)
End
109424876/108808420 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
CCDC138
Nearest miRNA
hsa-mir-1285-2/Upstream/6376054; hsa-mir-10b/Downstream/333070;
Nearest TSS
ENST00000437798/Upstream/16704; ENST00000609740/Downstream/48508;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/21310, chr2-CpG: 21/Downstream/134089
Upstream sequence
ctcctgcctcagcctcccaaagttctgggattacaggcatgacccaccAACGCTGGACTTTTAATTTTTGACGTTTTTAAAATTCTTCCTCTAGTCTAAT
Downstream sequence
ttgggaacctgaatacttgtgtttttcgtaatggctgtgctaatttatatccccaccaacaatgtaaaagagtttcccttctccacatcctcaccaacgt
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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