Basic Information
VIS ID
TVIS42000606
Fusion event
EBV-GPR39 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
98005
Orient
+
Integrated sequence
CGCAAACGGACTCAACGTGGTCTCCTTCTTTATCTCCATCCTGAAGCGAAGCAGCTCCGCCCTCACGGGCCATCTCCGTGAGTTGTTAACCACCCTGGAG| |ACTCTTTACGGTTCATTCTCAGTGGAAGACCTGTTTGGTGCCAACTTAAACAGATACGCATGGCATCGCGGGGGCTAGACCTCTGGCTGGATGAGCACGT
Host Sequence
Chromosome
chr2
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
133388993/132631420 (Hg38)
End
133388993/132631420 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
GPR39
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/197600; hsa-mir-10b/Downstream/1495705;
Nearest TSS
ENST00000437798/Upstream/26979; ENST00000450509/Downstream/29106;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/45611, chr2-CpG: 32/Downstream/13727
Upstream sequence
ccactgagggaatggggtcatcctccctagagaacctcggcggctgtgcggggatacggacaaaagccgctttgtggaagactgtgggaccgtccaacgg
Downstream sequence
TTAACAGGAAGGCATCCTCATCTGATCATTCTTGCCTCAAAACCCTATCTTAGAAGCCTGATACCATCTCAACCTTCCTGAGAGCTTTACTGATTTCTGT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate