Basic Information
VIS ID
TVIS42000614
Fusion event
EBV-SCN7A integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
103183
Orient
+
Integrated sequence
AGAAGGAGAGGGAGCTCTATCTAAAGAAGATCCGCTCCATGGAGTCTCAGCTGCAGGCCTCCCTGGGTCCCGGCGGCAACAACCCAGCGGCGTCAGCCCC| |CGCCGCAGTTGCGGCAGAAGCCGCGTCTGTAGATATACTGACGGGCAGCACCGCCTCCGCAATCGAAAAGCTGTTCAACTCCCCGTCCGCCAGCCTGGGT
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
167346529/166490019 (Hg38)
End
167346529/166490019 (Hg38)
Orient
-
Location type
Intronic
Target gene
SCN7A
miRNAs that regulate target gene
hsa-mir-7641 ; hsa-mir-8075 ; hsa-mir-210-5p ; hsa-mir-4695-3p ; hsa-mir-93-3p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-3675-3p ; hsa-mir-6769a-3p
Nearest miRNA
hsa-mir-128-1/Upstream/6082137; hsa-mir-10b/Downstream/2092924;
Nearest TSS
ENST00000437798/Upstream/3048; ENST00000409043/Downstream/4195;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/113818, chr2-CpG: 157/Downstream/802504
Upstream sequence
aaatcttccagcaccccaggacccaccttaaacccagccaacatcagccattcctatgggaatttgaaacctgtgtggactgaaggtaatgataatcaca
Downstream sequence
gtacgtatacacaaacattgtggaatgattatatcaagctaattaatatatccattatctcacagacttatttctttgtagtggaaacatttaaaatcta
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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