Basic Information
VIS ID
TVIS42000624
Fusion event
EBV-FTCDNL1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
10529
Orient
+
Integrated sequence
TCTTAGGAGCCCGGGCCAGCATTCTATCAGCTTAACGGGAAGAGAAGTGGGGAGGGCACTCGCCCACTAACCTTAACACCTGCAGCCTACAAAAGTACAC| |TAGCTGTTTGCTCTATTCGCCACTAGAGACCGCCAAGATGCGAAACTACAGGCCCGGGCCCAGGCCTTGCAGGGCAGACGGTTAGGCTGACAAGGGGACA
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
200575856/199711133 (Hg38)
End
200575856/199711133 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
FTCDNL1
Nearest miRNA
hsa-mir-10b/Upstream/10578022; hsa-mir-1244-1/Downstream/7072101;
Nearest TSS
ENST00000437798/Upstream/79402; ENST00000319974/Downstream/137837;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/51652, chr2-CpG: 85/Downstream/139532
Upstream sequence
ATTTATGTGTTCTGTCTGCCTGGGTTATGACTGAACCTCTTAGGACAGTTCCAGATGTCCATCAGAATTTCTCTTCCAAGTTGCTATTTTTAGAAGGTTT
Downstream sequence
GCTCTGAATACAGAGTGCCAAAATGCAGCCAGACTGAGCGAGGTATGGGCACATTACTAAAAATACAGGAAGAGTACAGTCAGGTGGCAACCTGAATTCA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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