Basic Information
VIS ID
TVIS42000629
Fusion event
EBV-MROH8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
151832
Orient
+
Integrated sequence
GTATCTGGCGGTGACTGTCACCTGGTTCTTGAGAGAGTCCATAAAATGGCTGAAGCTCCAGGCGTATAGTATAATGAGCAACAGGGCCAAACAGGCGGCG| |GGGCCTGGGTAGTAGCGGGCAACGAGAGACTCTGTGCAATCAAACCCCAGGCTCCCGGCCTCACCCAGGAAGAGCAGCGGCAGGGACAGCATAAACCAGG
Host Sequence
Chromosome
chr20
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
35777410/37149007 (Hg38)
End
35777410/37149007 (Hg38)
Orient
+
Location type
Intronic
Target gene
MROH8
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-222-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1694910; hsa-mir-1-1/Downstream/1367556;
Nearest TSS
ENST00000382410/Upstream/40343; ENST00000462163/Downstream/9897;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/52766, chr20-CpG: 70/Downstream/29999
Upstream sequence
attatgctgactgactgagggctgagttgcaagccccaccccctgccctgctcaactacaaggaccaagaaggggaatgaattcctctgggaacatcagc
Downstream sequence
gatctcattccttttatggctgaatagtacttcattgtgtataagaaccacattttctttatccattcatctgttggtggacacttaggctgcttccaaa
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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