Basic Information
VIS ID
TVIS42000631
Fusion event
EBV-TOX2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
84881
Orient
+
Integrated sequence
GCATAGAGAGTGATGAGCCCGCTTCGACAGAGCCGGTTCATGATCAGCTACTGCCTGCCCCAGGACCTGACCCTCTTGAAATCCAACCACTAACGTCCCC| |CACCACGTCTCAACTTAGCAGTTCGGCACCAAGCTGCGCACAAACTCCATGGCCGGTGGTTCAGCCAAGTCAGACTCCAGATGACCCAACGAAACAGTCC
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
42553511/43924871 (Hg38)
End
42553511/43924871 (Hg38)
Orient
+
Location type
Intronic
Target gene
TOX2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/2755793; hsa-mir-1-1/Downstream/483249;
Nearest TSS
ENST00000382410/Upstream/8704; ENST00000435864/Downstream/20834;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/8374, chr20-CpG: 79/Downstream/190811
Upstream sequence
aacaaacaaacaaagaaTGGGGCACTTGTTGTAAAACCCTTAGAGGataaaaaaaaaatttttaattGTCATTGCAAAAGCGACATTGTCCATCATACAA
Downstream sequence
TTCTCCACACACAGCCCTGTGTCCCGGGGTGTCCACTGAAAAGGGAGTGGAGGGTGTACTTCCCATCAAACCCtttcttcagttccttacttttaataca
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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