Basic Information
VIS ID
TVIS42000633
Fusion event
EBV-PREX1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
99453
Orient
+
Integrated sequence
CCCATAGACCTACGCGACCTGTACTTAGAGGCCCAGCTCCACGCCGCCCCCCTCCACCTTCAAGTCCCAATACATACAATAAACACATGATGGAAACCAC| |CCCCCCCATTAAGGGCAATAACAACTACAATTGGCCATGGCTGTAAATAAAATGTCATAACCTGGAGTCTGCATGTCTGTTGTTTTATTCAGTAAACCAG
Host Sequence
Chromosome
chr20
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
47400417/48783880 (Hg38)
End
47400417/48783880 (Hg38)
Orient
+
Location type
Intronic
Target gene
PREX1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1616822; hsa-mir-1-1/Downstream/1079979;
Nearest TSS
ENST00000382410/Upstream/91196; ENST00000493140/Downstream/44003;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/118775, chr20-CpG: 206/Downstream/43317
Upstream sequence
CTTCTGATTGCACAGGTAGCATTCAGAGAACCAATCTGAAACTGGTCTAAGTCCATACTAGTGTGCAAAAAGCAATTACTTGCTGATTGGTTGGGAAACT
Downstream sequence
AACAGCTCACCTGCTAATGTCCCCTCCATGTCTTTATGGATCTCACGCTCCTGAATATACCACAGTCACAACACAAGGTGAACGGAAAGCAAATCAGTTG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate