Basic Information
VIS ID
TVIS42000642
Fusion event
EBV-N6AMT1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
119074
Orient
+
Integrated sequence
AACGGCGCGGTGCAGTTGGTCACCAATGACGGCCTAAAGGCCAACACATCCTTGAAGCAGGGCGTAGGAATGGTACCAAACTCGGGGCCCACCCCATCAA| |AGACATAATATGTCTCATAGTGGCAGTGATGATGCATCACCACCACAGCACTCGCCAGGACCCTCTGCATATCTTGTACAAGGCGCCTTTCAACTCGGCC
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
30036476/28664154 (Hg38)
End
30036476/28664154 (Hg38)
Orient
+
Location type
Intronic
Target gene
N6AMT1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-99a-5p ; hsa-mir-183-3p ; hsa-mir-3120-5p ; hsa-mir-20b-3p ; hsa-mir-4680-3p ; hsa-mir-5187-3p ; hsa-mir-4427 ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929
Nearest miRNA
hsa-let-7c/Upstream/1710111; hsa-mir-3197/Downstream/1711140;
Nearest TSS
ENST00000624081/Upstream/37550; ENST00000399973/Downstream/10619;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1520167, chr21-CpG: 29/Downstream/220949
Upstream sequence
AATAAAGTATATTGCAAAATAAAACGTGTAGACATTAAAACTGGAATTAGTTTTATATGTGTTTACATTTGTCAAATCTTTTAGTAAGTTCTTTGATGCT
Downstream sequence
TGATTCTTTCATTTGTTTGAGTATAAGAAAATCTTTTACCCATATGGAAGCTTTACACATATTCCTAAGCCACATGGAATAGACACTTTGACTTGTATGC
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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