VISDB Viral Integration Site DataBase

VIS ID

TVIS42000643

Fusion event

EBV-TIAM1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

138017

Orient

+

Integrated sequence

GGGTCACATTGGGGATTATCAGAGAGACGGAGGTGTTGGAGTCATTTACCCATTCTAGGGTAAGGCTATAATTGTAACCCCCGTTAGTTATATGAGTTCC| |GTTGTTGGAAGTAGCTACGGCCAAGGGCAGTTGTCCATCCCCGGGAGTGTATCCCCGGCCCAACTCGATCCGAGAGACCGACTCATTGCTAGGAACGCTG

Chromosome

chr21

Cytoband

q22.11

Reference genome

Start

End

32638955/31266639 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-31-5p ; hsa-mir-335-5p ; hsa-mir-744-5p ; hsa-mir-93-3p ; hsa-mir-769-3p ; hsa-mir-615-3p ; hsa-mir-221-3p ; hsa-let-7b-5p ; hsa-mir-10b-5p ; hsa-mir-329-3p ; hsa-mir-141-3p ; hsa-mir-10a-5p ; hsa-mir-342-3p ; hsa-mir-29c-3p ; hsa-mir-22-3p ; hsa-mir-182-5p

Nearest miRNA

hsa-let-7c/Upstream/891261; hsa-mir-3197/Downstream/2284023;

Nearest TSS

Nearest CpG islands

None/Target, chr21-CpG: 261/Upstream/14573, chr21-CpG: 40/Downstream/77090

Upstream sequence

CCTCAGCCAAATATGTAGCGTCATCCCCGTAAAGCCTGCTCTCCTCAGTGTCTGGCATGCTCTGCACAGAGGCTGCTGTGAGGACGATGCTGCTGTCTAC

Downstream sequence

GCTGGGAGTGACAGAAGAGTCAGTGTAAGACACAGGTCTCAAGCCCATGTCCACTCGGTCCACCCAGATGGGGCTCCCGAAGTCTTCTAGGGTACCATCT