Basic Information
VIS ID
TVIS42000650
Fusion event
EBV-S100B integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
56350
Orient
+
Integrated sequence
CATTCTTGGACCGGACGGCCACGTTGTGGACAAAGGGGGGCACTGAGGCGGCGGGAGGGGCCCCATACTCTATCGCTGTCAACAGCGCCAAAAAGCGGAC| |GTCCTCCTCATCTACCCCAGCCTGTTGTCTGGCCACGGCCGTTCGGGCGGCCTCCGCCAGGGATAGGAGGCGCTTCCAGCTTTCGTCGTCCAGGACCAAG
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
48019435/46599522 (Hg38)
End
48019435/46599522 (Hg38)
Orient
+
Location type
Intronic
Target gene
S100B
miRNAs that regulate target gene
hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-296-5p
Nearest miRNA
hsa-let-7c/Upstream/1121196;
Nearest TSS
ENST00000624081/Upstream/35862; ENST00000491389/Downstream/3371;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/644, chr21-CpG: 83/Downstream/35765
Upstream sequence
TTCCTGGAAGTCACATTCGCCGTCTCCATCATTGTCCAGTGTTTCCATGACTTTGTCCACAACCTCCTGCTCTTTGATTTCCTAAGAGAGATAAAAGGAG
Downstream sequence
TTGCCGACCTTGTTTTTAAATGGAATTTTGGACCATCAAAACATGATTAAAAGTTGAGTGACTCTGATAATTTGTGTCCGAAATAACCTAAGAACATCAA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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