Basic Information
VIS ID
TVIS42000664
Fusion event
EBV-USP4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
127327
Orient
-
Integrated sequence
ACTGGGCCGTAACGCTAACTTTTTAACGAGGTGTAAGCATCAGGTTAATCTAAGACAGTCACCTATTTTCCTGACCCTCCTGAGGCACATCCGCCGACGT| |CTGGGCCTGGGCCGTGCTTCCGTAAAACGAGAGATTACCCTTCTCCTGGCCCACCTGCGCAAAAAGACAGCCCCCATCCACTGCCGTGATGCTCAAGTGT
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
49359754/49322321 (Hg38)
End
49359754/49322321 (Hg38)
Orient
+
Location type
Intronic
Target gene
USP4
miRNAs that regulate target gene
hsa-mir-148a-3p
Nearest miRNA
hsa-mir-12127/Upstream/48135; hsa-let-7g/Downstream/483816;
Nearest TSS
ENST00000440867/Upstream/3547; ENST00000497786/Downstream/17708;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/44939, chr3-CpG: 42/Downstream/17586
Nearest cancer related gene
USP4(OG, No orient, 0)
Upstream sequence
gtaagcttatgttttcttgacaaattcaggaaatttttagccattctttatttgaataccttttcagccacaccatctttctcttttccttccagttgtt
Downstream sequence
gcagtttatccatttacttttgatggacatttgggttagctccagtttgtaactatgacaagcagtgctagcacaaacatcctgaaatatgtatttaaga
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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