Basic Information
VIS ID
TVIS42000686
Fusion event
EBV-FGF12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
54949
Orient
-
Integrated sequence
GCAGGGTGTTCCAGTCATCGGGCGAAGTGGGAGCGGGCTCTGGGCGTGCCCCCAGCGCCTTCCTAATTCTGGCCCAGGCCTCATTCGCCTCTCGCGCTCG| |CCGCTCCTGCCTCTCCTTGTCTTCCTGTTCTCGGAGCTTCTCCTTTTCCTTGCGCCCGGTCTCCATAAGCTGCCGCAGCTTCTTCTCATACTGTCGCTTG
Host Sequence
Chromosome
chr3
Cytoband
q28
Reference genome
GRCh37/hg19
Start
192288985/192571196 (Hg38)
End
192288985/192571196 (Hg38)
Orient
+
Location type
Intronic
Target gene
FGF12
miRNAs that regulate target gene
hsa-mir-4668-5p ; hsa-mir-3613-3p ; hsa-mir-590-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-let-7g/Upstream/2741187; hsa-mir-3137/Downstream/2563310;
Nearest TSS
ENST00000440867/Upstream/54365; ENST00000264735/Downstream/156304;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/55848, chr3-CpG: 116/Downstream/345324
Upstream sequence
aaaaatgtactgatgtggtgggcctctgaattgccatagggtttatctcctattcattgtaacatgaatcttccaaaggactatatcatgctagccactt
Downstream sequence
CTCCTGGAAAGGCAACAATGACTTCGTGAAATCGTTTTCTGTGCTGTAGCAGAAAGGGAGGAATTCTGGAGGATCGCTCTTTCTGCAAACATCGCGGTCT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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