Basic Information
VIS ID
TVIS42000712
Fusion event
EBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
100586
Orient
+
Integrated sequence
GTGGGCCTCCACGAAGCTGTCCGCCTCGAGCGTGTCCATAAAGTCCCCGAAGGTGCCGGTATAGCCACAGATGGACTTTTTGGTCTTGCAGTTGACCGAC| |ACCGAGCTGTGCTTGACGTAGGTGACATTGTAGGTGACCTTGACCCGTTCTTCGTCCTGCTCGGTGCCCACCGGGACCATGTCTTGGTCGGCGAACTGCG
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
142317309/141396155 (Hg38)
End
142317309/141396155 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA4C
Nearest miRNA
hsa-mir-12113/Upstream/15888848; hsa-mir-1305/Downstream/1947305;
Nearest TSS
ENST00000502981/Upstream/63537; ENST00000608088/Downstream/34676;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/174950, chr4-CpG: 69/Downstream/240080
Upstream sequence
TGACAAGTAAATTAATATTACTCATTAGATCAGAGTTTAGATTACTGAGATATTTTACTCTTCGCTTATTTTTTGAATTCTGTACTATAAAATGTAAATA
Downstream sequence
gtccctaacaggttacaactggaagcggtccatgatcgaggggctggggacccctgCTTTAAGGGAAAAAAAGCTCCAATCTTGTCCTTGATTTCAGAAA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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