Basic Information
VIS ID
TVIS42000713
Fusion event
EBV-INPP4B integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
119444
Orient
-
Integrated sequence
CCGGGATAAGGGTGTAAACCTTGCAGAATGGATTGGTCGGACACCCATAAGACAGGGGCACCCCAAAATCACGCCCCTTACCCCGAAGCACCTTGGCCCC| |CACCGGCATAAAGCTGGGCAAAAAGAGTGGGTTAAAACCAAAGGCGAGTAGGGCCAGGAACGCCAAATAGCAGCAGTAATAGATGAAAACAAAGCTCAGC
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
143375055/142453902 (Hg38)
End
143375055/142453902 (Hg38)
Orient
+
Location type
Intronic
Target gene
INPP4B
miRNAs that regulate target gene
hsa-mir-222-3p ; hsa-mir-181a-5p ; hsa-mir-765
Nearest miRNA
hsa-mir-12113/Upstream/16946595; hsa-mir-1305/Downstream/889558;
Nearest TSS
ENST00000502981/Upstream/22643; ENST00000514766/Downstream/8826;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/816732, chr4-CpG: 111/Downstream/391885
Nearest cancer related gene
INPP4B(TSG, No orient, 0)
Upstream sequence
GTCAGTGGTTAAGTTTAAATATTCACTATGATGGCTACTCTGTCATTATAAAGGAAAATCTACCACTAACCAGAATGCCTGAAGAATATGAGGGCTTTGA
Downstream sequence
CATTCAGCATTTCTCTGAGCAACTCATGGGACTAGAGGAAATCATGGACTGATTTAACAAATGCCTTGTGAAACACGGGTTAATTCTCTGTGATGAACTG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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