Basic Information
VIS ID
TVIS42000727
Fusion event
EBV-GUSBP1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
121138
Orient
+
Integrated sequence
AACCACCTTATTTCCAAACTTTAATATTCTTCGTACCGGCGCCACCTCTTCAATTATATAGTGTCCGTAATGGATGGGGGCGTGGGTCTGTTTGACAGAC| |ATAAACTCATCGATGAGTGCCCGGGAGGAGGCTGAGAGTGCGGGGAATGCCTCCTGCAGAAAGCTGCAGGGCTGCTCCAGAAACACGTCAGTGCCAGCAA
Host Sequence
Chromosome
chr5
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
21469097/21468988 (Hg38)
End
21469097/21468988 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5E
Target gene
GUSBP1
Nearest miRNA
hsa-mir-10397/Upstream/4312996; hsa-mir-103a-1/Downstream/10467114;
Nearest TSS
ENST00000502646/Upstream/127613; ENST00000606105/Downstream/100767;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/9245, chr5-CpG: 68/Downstream/3721406
Upstream sequence
aacacatgggcatttttttctgataatacagaaaaattaattattcttatggaaccaacaatattaaattagtcttatttatcaaaaaagtcattcaaag
Downstream sequence
cgggttcaagcgattctcctgcctcagtgtcctgagtagctgggactacaggtgcacaccgccacacctggctaattttttgtattttagtagagacagg
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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