Basic Information
VIS ID
TVIS42000737
Fusion event
EBV-ADAMTS6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
94040
Orient
+
Integrated sequence
CGGGACAATCGCAATATAAAACCCTGACCATCACATGGGGCATTAGGCGACTCTGCATCAGCATCGCTTAAGTATGAGTGGGCAGCAGAGAGGCTCGGTT| |ATTTTGGTTCCTGAACATCTGGCTGGGGCATTAACTAAGCTTATGAGCGATTTTATCACAGGACAAGATGTCACTCTTTCTGGAGGAAATATTGCAGTCA
Host Sequence
Chromosome
chr5
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
64653139/65357312 (Hg38)
End
64653139/65357312 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADAMTS6
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-221-3p
Nearest miRNA
hsa-mir-10397/Upstream/5653609; hsa-mir-103a-1/Downstream/6812155;
Nearest TSS
ENST00000502646/Upstream/94375; ENST00000508982/Downstream/116361;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/253923, chr5-CpG: 43/Downstream/205636
Upstream sequence
caacatggacagtgccagaggccattatcctaaggaaactaatgcaggaacaggaaacttatttccacatgctctcacttataagtgttagctaaacatt
Downstream sequence
taagatgtaatgtgaaaacacaacataccaaaacttatgggatgcacactcttacatttgtaagaggaaagtatatagcaatagatacattaagaataaa
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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