Basic Information
VIS ID
TVIS42000746
Fusion event
EBV-PAM integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
113824
Orient
+
Integrated sequence
CATGTCCGGGTGCATTTTGGGTGGGTTAAATCTCAGTCCCACCACAAAGGGGGCATCCTCCGGTTTGAACATCAGACCCAACAAAGCCCGATGCCCAGTT| |ATGGGTACGTAGTCGTTGTTCAGGGCCGTGCATGGCAGCAGACAAGGACAGGTGCCAGATGTGCCTGGGCTATCGTCCTCCGTCCAGCCACGCAGGATGT
Host Sequence
Chromosome
chr5
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
102361837/103026133 (Hg38)
End
102361837/103026133 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
PAM
miRNAs that regulate target gene
hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-30c-5p ; hsa-mir-218-5p ; hsa-mir-34a-5p
Nearest miRNA
hsa-mir-10397/Upstream/2209568; hsa-mir-103a-1/Downstream/7487696;
Nearest TSS
ENST00000502646/Upstream/18564; ENST00000515845/Downstream/71560;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/159925, chr5-CpG: 33/Downstream/93716
Upstream sequence
gaaaaaaaaagaaagtaaagaaaagaaaaattatccaaccattatctggacatagtagcacgtgcctgtagtcctagctgctctggaggaggatcgtttg
Downstream sequence
AGGATCCAAGAGCTGAGTTTATTTTAGGACATCTAAATAAATAAACAACCCAATTCATGTTTCTTACCGCTCAGTAGCAGTCCCTTGGCTGGGTCCCCAG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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