Basic Information
VIS ID
TVIS42000770
Fusion event
EBV-KHDRBS2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
5887
Orient
-
Integrated sequence
AGCTGGACGTGAACCTCCCCCCCAGACCTGTGTGCTGTATTTACAAACACTACAATAAACCCAATGTGCAAATGTGGTTTGTATGGCTACTTTGTGTTCC| |TAAAAAATGCAACAATAGAAGTGGAAACCCTCAGTCACGGGACATTAACCTCAACCACAAAATGGGGGTTGGAGAAAGTAACCACATATACTGGAGATGA
Host Sequence
Chromosome
chr6
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
62895020/62185115 (Hg38)
End
62895020/62185115 (Hg38)
Orient
+
Location type
Intronic
Target gene
KHDRBS2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10398/Upstream/4794903; hsa-mir-10524/Downstream/9191845;
Nearest TSS
ENST00000381078/Upstream/1461967; ENST00000370659/Downstream/101112;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/4223565, chr6-CpG: 45/Downstream/100835
Upstream sequence
aataGAATGACCTTTACTTAACATTATCTGAAACTGAACAGCCTATACTATAGAAAATAATTACTAATGCTGAGCTACTGCAAATATTACCATAATTGTT
Downstream sequence
TGCATTGTTGTCTGGCAATAATTATTGCATTGTTTTGATATTATTACACCTCACATTTGTCTCCCTGTATTTTGTAACCTCTTAGCAGGAAGTTTATTTT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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