VISDB Viral Integration Site DataBase

VIS ID

TVIS42000782

Fusion event

EBV-PRDM1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

150777

Orient

-

Integrated sequence

GGCGTCGTGCTCCGGGTGGAGGGGGAATAGCGTCCAGGCATCTTTCAGGGTCACGAGACCGGGGTCCATGCTCAGAGAACAGCCCTCCCGGGCGGTGGGC| |GGCCCGGGCTCCAGCAGAACGTCGCAGACCCAGCCCTCCTCGGCCCTGTCCACCTGTATGTCCAGGTGCACGGACCCGGAGGCTGCGTCTCGTGACATGG

Chromosome

chr6

Cytoband

q21

Reference genome

Start

End

106550460/106102585 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7a-5p ; hsa-mir-9-5p ; hsa-mir-127-3p ; hsa-mir-125b-5p ; hsa-let-7b-5p ; hsa-let-7f-5p ; hsa-mir-30a-5p ; hsa-mir-877-3p ; hsa-mir-223-3p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-125a-3p ; hsa-mir-374a-5p ; hsa-mir-129-5p ; hsa-mir-125a-5p ; hsa-mir-140-5p ; hsa-mir-874-3p ; hsa-mir-3157-3p ; hsa-mir-6886-3p ; hsa-mir-938 ; hsa-mir-222-3p ; hsa-mir-101-3p ; hsa-mir-320c

Nearest miRNA

hsa-mir-10398/Upstream/6977889; hsa-mir-1202/Downstream/681540;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/16075, chr6-CpG: 56/Downstream/222727

Nearest cancer related gene

PRDM1(TSG, No orient, 0)

Upstream sequence

tcttaccacttctcagcttcatagctgtatcttctccctacaactcaattatgtcattactggtcttgtttactggtctcactgcttccccaccctcacc

Downstream sequence

ATATCAGTTCAACATTCAAATTATATTAAGGTACTTAAGAAGAATCCCTGGCTAAATGTGAGGGGCAGTGCCACAGATGGACTGAAACTTTATGCTTATT