VISDB Viral Integration Site DataBase

VIS ID

TVIS42000796

Fusion event

EBV-WIPI2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

42389

Orient

+

Integrated sequence

CTTGGAACAGATTTATAACACACACCGAACATGTGGATCTGGATTTTAACTCAGTATTTTTAGAGATATTTCACCGTGGAGACCCAAGCCTTGGGCGCGC| |GTTGGCCTGGATGGCCTGGTGCATGCATGCCTGCAGGACATTGTGTTGTAACCAGTCTACTCCTTACTATGTTGTGGACCTGTCAGTTCGTGGGATGTTA

Chromosome

chr7

Cytoband

p22.1

Reference genome

Start

End

5244939/5205308 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-505-5p ; hsa-mir-615-3p ; hsa-let-7a-5p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-3908 ; hsa-mir-3909 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-6507-3p ; hsa-mir-6780a-3p ; hsa-mir-6838-5p ; hsa-mir-6852-3p ; hsa-mir-3611 ; hsa-mir-7843-3p ; hsa-mir-4786-3p ; hsa-mir-4679 ; hsa-mir-4677-3p ; hsa-mir-103b ; hsa-mir-646 ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-503-5p ; hsa-mir-575 ; hsa-mir-4676-5p

Nearest miRNA

hsa-mir-339/Upstream/416669; hsa-mir-10399/Downstream/290511;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/14598, chr7-CpG: 28/Downstream/21982

Upstream sequence

tctttcttactttttcgttttgttttgttttgttttgttgtttgtttgtatttttgagacagagtcttgctctgttgccaggctggagtgcagtggtgct

Downstream sequence

TGTTCACTCCAGAGTGATTGGTCGTTCATTTCTGCCTTTTGCAGAGCCACCTCTCCTACttttggttactgactcttgtaaatgtgatgagagttataga