VISDB Viral Integration Site DataBase

VIS ID

TVIS42000814

Fusion event

EBV-ADAM22 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

112609

Orient

+

Integrated sequence

GGAAGCTCTTGAGTGGCGTCTCCACCAGCTTAAATTGCTCGGGCGTGTCCTGGCAGGCCTCCAGTGCCAGTTCCAGACACTGCCCATACCTGCGGGCGAG| |CATCGGGTCATCGGGCATATCGGCCTTGACCGCGTTGAACATGCTGTATGCCTCGCAGCGCGGCCGTCTGACCGAGAACCTAAGAAACGCCCTTCAGCAG

Chromosome

chr7

Cytoband

q21.12

Reference genome

Start

End

87679060/88049745 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-539-5p ; hsa-mir-451b ; hsa-mir-624-5p ; hsa-mir-5581-3p ; hsa-mir-5701 ; hsa-mir-4716-5p ; hsa-mir-6782-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-3148 ; hsa-mir-33b-3p ; hsa-mir-3692-5p ; hsa-mir-371a-3p ; hsa-mir-371b-3p ; hsa-mir-4704-5p ; hsa-mir-515-3p ; hsa-mir-519e-3p ; hsa-mir-5580-5p ; hsa-mir-570-3p ; hsa-mir-6080 ; hsa-mir-6124

Nearest miRNA

hsa-mir-10525/Upstream/12134476; hsa-mir-10399/Downstream/4154270;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/114489, chr7-CpG: 59/Downstream/169943

Upstream sequence

GGACACTTGTTGGGGAGTCAGTCTGCGCTTCTGGCATCTGGACACATCAGCCTATATCTCTAGGACTCGAGCAGGAAGTATGTTTGCCTCGCCTCGGGCT

Downstream sequence

GAAAGGGATGATTTTTACCTTGATCATAAATTGAGAAATCTAAGGTTAGAGTTAGTGAATGGTATATAGATTCTTTTTTATTTTTGGTCAGCAGATGtta