VISDB Viral Integration Site DataBase

VIS ID

TVIS42000824

Fusion event

EBV-CFTR integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

72777

Orient

-

Integrated sequence

GGCAGCCGGATGCACCGCCCGGCGTGATACACGCCGCTGTCAAAAAGCGGGGCCCCAATCTCTTTGATCTTGTGACGCATGCGGCGCAGGCAGGCCGTTA| |GGCCCATGAGCTTCTGCAGCACAGACACAAACCCTTGTACTGCGCTTGTTCCCACAATAGCATGGCCTCTAGGTAGGGGGGTGATGACGCGAAAGCCCAG

Chromosome

chr7

Cytoband

q31.2

Reference genome

Start

End

117309035/117668981 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-433-3p ; hsa-mir-509-3p ; hsa-mir-335-5p ; hsa-mir-132-3p ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-494-3p ; hsa-mir-223-3p ; hsa-mir-145-5p

Nearest miRNA

hsa-mir-10525/Upstream/648662; hsa-mir-10399/Downstream/9389107;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/241369, chr7-CpG: 92/Downstream/203907

Nearest cancer related gene

CFTR(TSG, No orient, 0)

Upstream sequence

taagagctcaaccaatgttagATGCTGTTCTTGTTGCTCTCTTCCCCCTTCCTCCCTTTTCTTCCTCCTTTTCACTTTTTCCTTtcctctcccttctccc

Downstream sequence

caataatcccgcatttatctttcctctaatgcctggcaaccaccattttactttctgtctctgattttgactactcgaaggacctaggagtgggatcata