Basic Information
VIS ID
TVIS42000834
Fusion event
EBV-DPP6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
140138
Orient
+
Integrated sequence
TGGTCCAATCCATAGGCTTTTTTTGTGAAAACCCGGGGATCGGACTAGCCTTAGAGTAACTCAAGGCCAAGCATTTCACACCTGCAAATGCACCATGTAA| |CCACAGATCTAAACTGAAAGTTGCAGCTTTAGATGGCAAGGAAACTTGGGTTTCAGGCATAGAAAGCCTGGCTCACTATAGCAGCCCATGTTTGTTCCAG
Host Sequence
Chromosome
chr7
Cytoband
q36.2
Reference genome
GRCh37/hg19
Start
154683262/154891552 (Hg38)
End
154683262/154891552 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
DPP6
miRNAs that regulate target gene
hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-4668-5p ; hsa-mir-3153 ; hsa-mir-513b-3p ; hsa-mir-1276 ; hsa-mir-497-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-511-5p ; hsa-mir-6830-3p
Nearest miRNA
hsa-mir-10399/Upstream/3457913; hsa-mir-153-2/Downstream/2682784;
Nearest TSS
ENST00000635602/Upstream/7984; ENST00000397551/Downstream/36933;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/96926, chr7-CpG: 19/Downstream/1140
Upstream sequence
GTTTAAAAACATGAAACTACAGATAAGTTACTGATTTAAAAATTTGTCTTTTCTTTCTATTATCAAAAACTTTGAAAAGTATTTATTTCCGTCTGTATGC
Downstream sequence
GGTGGGCCCGTGGGCACCCAGGACAGCACGCAGCCCTTCCACGGGAGTTTCCCACACTCAGAGTGTAACTGAGAGAGCATAggagtgtaatggcgcgatc
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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