Basic Information
VIS ID
TVIS42000836
Fusion event
EBV-WDR60 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
57759
Orient
+
Integrated sequence
GCAGTCGGGGAAGGGGATGGGGTGGTCAGAGGGATTTTTGGGTTCGAGGGAGCTGCCTGTGGCAGAGGGATGGGTATTTGCAAAGGGAGGCGAGGAGATG| |GAGTGACTGAAGGAGCGATAGTTGAGACTGGCGCGGGGTGGGGTGTCGGGGAGGCGGGTGGTGATTGGTGAGGGATGGGGATTACTGGAGGGGGAAGGCG
Host Sequence
Chromosome
chr7
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
158705427/158912736 (Hg38)
End
158705427/158912736 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
WDR60
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-331-3p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10399/Upstream/321040;
Nearest TSS
ENST00000635602/Upstream/28162; ENST00000454771/Downstream/21457;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/35422, chr7-CpG: 38/Downstream/7132
Upstream sequence
gcaccaccatgcccggctaatttttgtatttttagtagagacagagtttccccatgttggccaggctggtctcaaactcttgacctcgggtgatccaccc
Downstream sequence
TGGGCAGGTGAGGTGGCAGTATTTTCAGACTAAAGGGAAATCGTTTGGTGAGACTTTTTGAACACACTTTTGAAAATTAGACCTGTATATATCTATATCG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate