VISDB Viral Integration Site DataBase

VIS ID

TVIS42000840

Fusion event

EBV-PIWIL2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

68095

Orient

+

Integrated sequence

CTATGGAATATGATGATAAGGTGTCCAAGAGCCACCACACCTGCGCCCTGATGCCCTATATGCCCCCGGCCAGCGACAGGCTGAGGAACGAGCAGATGAT| |TGGGCAGGTGCTGTTGATGCCCAAGACGGCTTCCTCGTTGCAGAAGTGGGCACGCCAGCAAGGCTCAGGCGGCGTTAAGGTGACACTCAATCCGGATCTC

Chromosome

chr8

Cytoband

p21.3

Reference genome

Start

End

22160603/22303090 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-4795-5p ; hsa-mir-4775 ; hsa-mir-93-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-455-5p ; hsa-mir-590-3p ; hsa-mir-8485 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-497-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-6888-3p ; hsa-mir-452-3p ; hsa-mir-3120-5p

Nearest miRNA

hsa-mir-124-1/Upstream/58053; hsa-mir-10400/Downstream/2650706;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/27246, chr8-CpG: 83/Downstream/63916

Nearest cancer related gene

PIWIL2(TSG, No orient, 0)

Upstream sequence

tgattgagctatgccctcaattgttgatatataggtttttaattgtcacttagctctaaattgttccttattcccccataccattaccattttgacccaa

Downstream sequence

gactggtagttaccagatctagggaaggagggggagtgtgaatataaagggcagcaggaaatagtcccttggtggtgacatgcaacagtttggtatctga