Basic Information
VIS ID
TVIS42000873
Fusion event
EBV-MOB3B integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
102292
Orient
-
Integrated sequence
CGAGCGATGACTCGTGTGCGAGCCGGTTTCGTGAGTCCACCTTCGAGTCGTGGTCCACGACCATGAAGCTGACCGTGCGTGACCTGCTGACCACCAACAT| |CTACCGAGTGCTACACAGCCGCTCCGTGCTCTCCTATGAGCGTTATGTGGACTGGATCTGCGCCACCGGCATGGTGCCCGCCGTTAAGAAGCCCATAACC
Host Sequence
Chromosome
chr9
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
27416327/27416329 (Hg38)
End
27416327/27416329 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
MOB3B
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-122-5p ; hsa-mir-181a-5p ; hsa-mir-98-5p ; hsa-mir-4776-3p ; hsa-mir-192-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-2114-5p ; hsa-mir-4307 ; hsa-mir-33a-3p ; hsa-mir-409-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-1227-3p ; hsa-mir-455-5p ; hsa-mir-148a-5p
Nearest miRNA
hsa-mir-101-2/Upstream/5904144; hsa-let-7a-1/Downstream/1447297;
Nearest TSS
ENST00000422679/Upstream/24595; ENST00000276943/Downstream/5385;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/459557, chr9-CpG: 27/Downstream/112030
Upstream sequence
gacaccaaggcttacggcctgcaccttcttaagcagtgtcctcaactgtacttgggcccattttagctacagctggagctgctggggtgcagggagcagt
Downstream sequence
aaggaagaacagcaggtgcaaagtcctcggggaggctaggcgtggcggctcacgcctgtaatctcagcatgttgggaagccaaggcaggaggattgcttg
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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