VISDB Viral Integration Site DataBase

VIS ID

TVIS42000896

Fusion event

EBV-DMD integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

121471

Orient

+

Integrated sequence

GCTGTAGAGGCCCGGGACGGCCGTCTGGCGATAGGAGGAGTTGTACATGATGTCACCCAGAGAACCCAGCTGAGATGCCCAGGGATTCACAGTGCTCCGG| |TATTCATAGGCGGCATCCGGGCGAGAATGGTCATAGATGAGCCCCTCGGCAACCTCCTGATTGTAGTTTTCACAGGAGACCACACAGGCGGCCCGTCCCC

Chromosome

chrX

Cytoband

p21.1

Reference genome

Start

End

31765531/31747414 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-31-5p ; hsa-mir-155-5p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-4446-5p ; hsa-mir-186-3p ; hsa-mir-561-3p ; hsa-mir-6499-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-297 ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-8068 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-511-3p ; hsa-mir-9-3p

Nearest miRNA

hsa-mir-23c/Upstream/2173056; hsa-let-7f-2/Downstream/836242;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/480512, chrX-CpG: 36/Downstream/1978899

Nearest cancer related gene

DMD(TSG, No orient, 0)

Upstream sequence

tgagggaaaggagctatcgttaactgCAGTGTTGTTAAAAAAAAGAGGATGAATTTGGAGATGCATTATGATGACTATGTATTTATAATGGGAAGGAGAA

Downstream sequence

ACTTACAGTATGACAGCTTTTAAAGGAAGGGACATATTCTATGGGGAGGATTTTAGACATACTTGTCTATTCCCTAGGCCGTACTAATTCTTATCATATA