Basic Information
VIS ID
TVIS42000942
Fusion event
EBV-NHEJ1 integration
Validated
Yes
Detection method
Sanger sequencing
Data source
Curated
Sample type
Tumor
Disease
Extranodal natural killer T-cell lymphoma (NKTCL)
Quality evaluation
Perfect
Reported year
2018
PubMed ID
30546078
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
6955
End
7064
Orient
+
Integrated sequence
AGGACAGCCGTTGCCCTAGTGGTTTCGGACACACCGCCAACGCTCAGTGCGGTGCTACCGACCCGAGGTCAAGTCCCGGGGGAGGAGAAGAGAGGCTTCCCGCCTAGA
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
219973787/219109048 (Hg38)
End
219973770/219109065 (Hg38)
Orient
+
Location type
Exonic
Target gene
NHEJ1
Nearest miRNA
hsa-mir-10b/Upstream/50298; hsa-mir-1244-1/Downstream/185046;
Nearest TSS
ENST00000437798/Upstream/39239; ENST00000465672/Downstream/15699;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/47640, chr2-CpG: 68/Downstream/50963
Upstream sequence
TAGAATAAGAGTGAGATA
Downstream sequence
AGAATAAGAGTGAGATATCT
Target sequence
AGAATAAGAGTGAGATA
Junction sequence
TAGAATAAGAGTGAGATAAGGACAGCCGTTGCCCTAGTGGAAGAGAGGCTTCCCGCCTAGAGAATAAGAGTGAGATATCT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Peng, R. J., et al. Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma. Leukemia,2018
Curate