Basic Information
VIS ID
TVIS42000943
Fusion event
EBV-chr20:q13.32 integration
Validated
Yes
Detection method
Sanger sequencing
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Perfect
Reported year
2019
PubMed ID
30867819
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
121107
Orient
+
Integrated sequence
TCAAATCCATCTTTATTGACAATTATCAAAAAACCACCTTATTTCCAAACTTTAATATTCTTCGTACCGGCGCCACCTCTTCAATTATATAGTGTCCGTA| |ATGGATGGGGGCGTGGGTCTGTTTGACAGACATAAACTCATCGATGAGTGCCCGGGAGGAGGCTGAGAGTGCGGGGAATGCCTCCTGCAGAAAGCTGCAG
Host Sequence
Chromosome
chr20
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
57967350/59392295 (Hg38)
End
57967350/59392295 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/573982; hsa-mir-1-1/Downstream/916179;
Nearest TSS
ENST00000382410/Upstream/27522; ENST00000443747/Downstream/122896;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/91224, chr20-CpG: 31/Downstream/11451
Upstream sequence
CTCAACTACAAGGACCAAGAAGGGGAATGAATTCCTCTGGGAACATCAGCA
Junction sequence
CTCAACTACAAGGACCAAGAAGGGGAATGAATTCCTCTGGGAACATCAGCAAATGGATGGGGGCGTGGGTCTGTTTGACAGACATAAACTCATCGATGAGTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Xu, M., et al. Genome-wide profiling of Epstein-Barr virus integration by targeted sequencing in Epstein-Barr virus associated malignancies. Theranostics,2019,9(4): 1115-1124.
Curate