VISDB Viral Integration Site DataBase

VIS ID

TVIS42000955

Fusion event

EBV-PPM1D integration

Validated

No

Detection method

GenCap Enrichment+NGS

Data source

Curated

Sample type

Disease

Gastric carcinoma (GC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

EBV

Reference genome

Start

65822

Orient

+

Integrated sequence

ACTTCACACCAGGAAGATTTTTCCGGGTTTCAAACAGAGCAAGTATGCCGGGGGGTGGTTTCACTGGCACGATTGGGCAGGAACAGACCTTTCTATTCCC| |AGGGAAATTTGGTCTCGCCTCTCTGAACGCATTGTGAGGGATGGGCTTTTCAATTCACAGTTTATCGCCCTGATGCCCACCTCAGGCTGTGCCCAGGTGA

Chromosome

chr17

Cytoband

q23.2

Reference genome

Start

End

58680377/60603016 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-29a-3p ; hsa-mir-16-5p ; hsa-mir-153-3p ; hsa-mir-145-5p ; hsa-mir-203a-3p ; hsa-mir-217 ; hsa-mir-26b-5p ; hsa-mir-29c-3p ; hsa-mir-450a-1-3p ; hsa-mir-15b-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-6785-5p ; hsa-mir-7106-5p ; hsa-mir-149-3p ; hsa-mir-138-5p ; hsa-mir-3135a ; hsa-mir-342-3p ; hsa-mir-645 ; hsa-mir-383-3p ; hsa-mir-1228-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4746-3p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-4687-5p ; hsa-mir-593-5p

Nearest miRNA

hsa-mir-10226/Upstream/559911; hsa-mir-1250/Downstream/2341199;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/2160, chr17-CpG: 56/Downstream/74248

Nearest cancer related gene

PPM1D(OG, No orient, 0)

Upstream sequence

AATATTCAGCTAAATTAAACCTGAACTTGGTAGTCAGTGGTTGTGTTGTTTAAAAAGGCCTCTGTACTTCCCTCCGGCCTATATCAATGACATGTTTTGT

Downstream sequence

ACACATGGAAATACTCCATTTCCATTTTCTTGGATTCTGCCTCTCTCACCCTGCCCCCCCAACAAGGAAAACTCAAACAAAAATATATCCATCATGTAGA