VISDB Viral Integration Site DataBase

VIS ID

TVIS42000969

Fusion event

EBV-ACTR3B integration

Validated

No

Detection method

GenCap Enrichment+NGS

Data source

Curated

Sample type

Disease

Gastric carcinoma (GC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

EBV

Reference genome

Start

97564

Orient

-

Integrated sequence

GATGGAGTAGATTTGCCTCCCTGGTTTCCACCTATGGTGGAAGGGGCTGCCGCGGAGGGTGATGACGGAGATGACGGAGATGAAGGAGGTGATGGAGATG| |AGGGTGAGGAAGGGCAGGAGTGATGTAACTTGTTAGGAGACGCCCTCAATCGTATTAAAAGCCGTGTATTCCCCCGCACTAAAGAATAAATCCCCAGTAG

Chromosome

chr7

Cytoband

q36.2

Reference genome

Start

End

152612883/152915798 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-379-3p ; hsa-mir-487a-3p ; hsa-mir-539-3p ; hsa-mir-127-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-4710 ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-621 ; hsa-mir-4660 ; hsa-mir-6804-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-5690 ; hsa-mir-6760-5p ; hsa-mir-4779 ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p

Nearest miRNA

hsa-mir-10399/Upstream/1482159; hsa-mir-153-2/Downstream/4658538;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/11933, chr7-CpG: 20/Downstream/9033

Upstream sequence

CCTCCGAAAGgagagagagtgggggagagagggcaggagaggagggagcggcggaggacgggaAATGGTGGCGGTAATGAGATTTTGGAAGCCACAGCGC

Downstream sequence

ccttctcaccctccttctccttctcctccccctcccctcatctcctcctcctcATTTTTTCCTCTTATTCTTGGCCAGGCTGGGGTGCTGGGACAGAGCA