Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene105371795104641101105265235105006448
SORCS3 _STAD.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS42000984
Fusion event
EBV-SORCS3 integration
Validated
No
Detection method
GenCap Enrichment+NGS
Data source
Curated
Sample type
Tumor
Disease
Gastric carcinoma (GC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25355872
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
115496
Orient
+
Integrated sequence
TGGGTGGTGCTTGGACACAGAGGTCTCAGCAGCCGCCTTGGTCTCGGCCCCGGCCCTAAGTCTGAGCCCCAGGCAAAGGGCCGGACTCCCAGCGTGGCCC| |AACCTCTGCTCCCCTCTATTCTCCTCTTGCGTTATCTCCAATAGAATTTGCTTGAGGTCATACGTTTTAGGGTGCTCGACCTGGGCCGCGGCCACCGGCA
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
106766206/105006448 (Hg38)
End
106766206/105006448 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
SORCS3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-107/Upstream/738043; hsa-mir-202/Downstream/5891642;
Nearest TSS
ENST00000439456/Upstream/340248; ENST00000393176/Downstream/152480;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/363394, chr10-CpG: 100/Downstream/2157574
Upstream sequence
AGGGCTGGGCTTGGAGGGTGGCCACCTCCTCCTGAAGATGTGTCAGCGCCTCCTTTAACATTCTAGGCAGATCCTGACCAGACTCTGCGGCACCCAGCCA
Downstream sequence
AATCTCCTAAATCCAGACTGTTTATTCCAGAGATCAGGGTGTGTGTCTTCCACATCTTCCTCCACCCTTGACTTCCTTTGCAGGGTTTCGTGGCTGGAGC
Reference
Cao, S., et al.High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol,2015, 89(1): 713-729.
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