VISDB Viral Integration Site DataBase

VIS ID

TVIS42000991

Fusion event

EBV-MAP3K12 integration

Validated

No

Detection method

GenCap Enrichment+NGS

Data source

Curated

Sample type

Disease

Gastric carcinoma (GC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

EBV

Reference genome

Start

93845

Orient

+

Integrated sequence

CCTGACTGCGCTGAATACATAGACCTACTAAAGCACACAAAACATGTCTTAGAAAACTGTTCTGCCATGCAATACAAATAAATTTCTCTTACCTGCGTCT| |GTTTGTGTAGTGAGGTGTTGTGTCCTGTATGGTATTCTACTTTAAAAAGGCCGGCTGACATGGATTACTGGTCTTTTATGAGCCATTGGCATGGGCGGGA

Chromosome

chr12

Cytoband

q13.13

Reference genome

Start

End

53892705/53498921 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-26b-5p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-32-3p ; hsa-mir-6722-5p ; hsa-mir-130a-3p

Nearest miRNA

hsa-mir-1244-3/Upstream/441909; hsa-let-7i/Downstream/492817;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/5708, chr12-CpG: 37/Downstream/490

Upstream sequence

cctctaaaatcagggtaaggataaatttcttattcaataaaatgacataaggacaggtgagtagtcaaagtaaaaaaatgtacactcattctccacgcca

Downstream sequence

aaataattttgatttttacacaggaaaaaataaaaccattaagccactaaaaatatgggggaatatttttaGAATTTCATATTTTAAGTATAACACAAAA