VISDB - VIS Detail

Basic Information

VIS ID

TVIS42001084

Fusion event

EBV-ERCC6L2 integration

Validated

Detection method

GenCap Enrichment+NGS

Data source

Curated

Sample type

Tumor

Disease

Gastric carcinoma (GC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

25355872

Virus Sequence

Virus name

EBV

Reference genome

NC007605

Start

117246

Orient

Integrated sequence

ATCGGCAAGATTTTGACATGCAGGACAGCATGGTCTCATGCCCCTGCTTTCGCCTGCACATCCCGTCCTACATCACCATGGACAGCAACATCCGAGCAAC| |CACCAACCTCTTTCTGGACGGGGCCTTTAGCACCGAGCTGATGGGTGACACCTCCTCGCTGAGCCAGGGTAGCCTGAGCCGCACTGTGCGTGACGATGCC

Host Sequence

Chromosome

chr9

Cytoband

q22.32

Reference genome

GRCh37/hg19

Start

98781695/96019413 (Hg38)

End

98781695/96019413 (Hg38)

Orient

Location type

Intronic

Target gene

ERCC6L2

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-3162-3p ; hsa-mir-6771-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7154-3p ; hsa-mir-5004-5p ; hsa-mir-383-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-3714 ; hsa-mir-122-3p ; hsa-mir-1915-3p ; hsa-mir-1976 ; hsa-mir-2276-3p ; hsa-mir-3194-3p ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4726-3p ; hsa-mir-5001-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6764-5p ; hsa-mir-6778-3p ; hsa-mir-6791-3p ; hsa-mir-6796-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6840-3p ; hsa-mir-6890-3p

Nearest miRNA

hsa-let-7a-1/Upstream/933319; hsa-mir-12126/Downstream/1344141;

Nearest TSS

ENST00000422679/Upstream/46576; ENST00000432783/Downstream/2347;

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/143250, chr9-CpG: 122/Downstream/1521

Upstream sequence

CCTCTTCCTTTTATTTCTTGCTAGAGGATTCTACAAGAAATATaactccacttccaagtatctactctagagaagcattttgccaatgtctacgataagg

Downstream sequence

AGCAGCCGGGGACAGAGCTCCAGACCCCGCAGGCTGGCTGGGCTGAAAGGTAGCCCCCAAAGACATGACCACCTCATGCCCCCTGGTGCAgccaccagcc

Reference

Cao, S., et al.High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol,2015, 89(1): 713-729.